Lee Blackett has named his side to travel to Bristol in Gallagher Premiership Round 18 on Friday.
There are three personnel changes and one positional switch from the team that played Harlequins last Saturday.
James Gaskell makes his 150th Wasps appearance, as he starts at blindside flanker. Gaskell is joined by the Willis brothers in the back row. Jack Willis makes his first start of the season, having come off the bench last week.
Club Captain Joe Launchbury returns from England training camp to start in the second row, alongside Elliott Stooke.
The only other change sees Gabriel Oghre come in at hooker for the injured Tom Cruse. Oghre is flanked in the front row by Biyi Alo and Tom West, who signed a new contract with the Club this week.
The backline is unchanged from last weekend, Ryan Mills and Sam Spink form the centre partnership.
Jacob Umaga is at full-back and is joined by Paolo Odogwu and Josh Bassett in the back three.
Dan Robson and Charlie Atkinson form the half-back pairing once more.
On the bench, Marcus Watson is in line to make his 50th Premiership appearance for Wasps. Alfie Barbeary also returns to the squad, having been released from the England squad. They are joined by Michael van Vuuren, Ben Harris, Jeffery Toomaga-Allen, Nizaam Carr, Will Porter and Jimmy Gopperth as the other replacements.
Wasps team to face Bristol Bears at Ashton Gate Stadium on Friday (kick-off 7:45pm)
Wasps (First-team appearances)
1 Tom West (65)
2 Gabriel Oghre (59)
3 Biyi Alo (31)
4 Joe Launchbury (163) (c)
5 Elliott Stooke (17)
6 James Gaskell (149)
7 Jack Willis (67)
8 Tom Willis (53)
9 Dan Robson (147)
10 Charlie Atkinson (25)
11 Josh Bassett (168)
12 Ryan Mills (9)
13 Sam Spink (17)
14 Paolo Odogwu (29)
15 Jacob Umaga (61)
Replacements
16 Michael van Vuuren (6)
17 Ben Harris (83)
18 Jeffery Toomaga-Allen (59)
19 Nizaam Carr (69)
20 Alfie Barbeary (23)
21 Will Porter (45)
22 Jimmy Gopperth (145)
23 Marcus Watson (65)
Unavailable (
: Tom Cruse, Malakai Fekitoa, Vaea Fifita, Dan Frost, Robin Hislop, Rodrigo Martinez, Brad Shields, Thomas Young.