Lee Blackett has named his side to travel to Gloucester in Gallagher Premiership Round 22 on Saturday.
There are three personnel changes and one positional switch from the win against Newcastle Falcons last weekend.
Will Porter makes his 50th Wasps appearance as he starts at scrum half. Porter forms the half-back partnership with Charlie Atkinson.
Atkinson’s return sees Jacob Umaga move to full back. Umaga is joined in the back three by wingers Paolo Odogwu and Josh Bassett.
The front row is made up of Tom West, Gabriel Oghre and Biyi Alo.
Malakai Fekitoa starts at outside centre. He forms the centre partnership with Jimmy Gopperth.
Brad Shields joins Alfie Barbeary and Jack Willis in an unchanged back row, while Elliott Stooke lines up alongside captain Joe Launchbury in the second row.
Amongst the replacements Zach Kibirige is in line to make his 50th Premiership appearance for Wasps. He is joined on the bench by Dan Frost, Ben Harris, Elliot Millar-Mills, Vaea Fifita, Tom Willis, Dan Robson and Sam Spink as the other replacements.
Wasps team to face Gloucester at Kingsholm on Saturday (kick-off 3:00pm)
Wasps (First-team appearances)
1 Tom West (68)
2 Gabriel Oghre (62)
3 Biyi Alo (34)
4 Joe Launchbury (165) (c)
5 Elliott Stooke (20)
6 Brad Shields (72)
7 Jack Willis (70)
8 Alfie Barbeary (25)
9 Will Porter (49)
10 Charlie Atkinson (28)
11 Josh Bassett (171)
12 Jimmy Gopperth (148)
13 Malakai Fekitoa (42)
14 Paolo Odogwu (33)
15 Jacob Umaga (64)
Replacements
16 Dan Frost (13)
17 Ben Harris (85)
18 Elliot Millar-Mills (10)
19 Vaea Fifita (16)
20 Tom Willis (57)
21 Dan Robson (150)
22 Sam Spink (19)
23 Zach Kibirige (60)
Unavailable (6): Tom Cruse, James Gaskell, Francois Hougaard, Michael Le Bourgeois, Rodrigo Martinez, Jeffery Toomaga-Allen.